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Niacinamide

Niacinamide, also known as vitamin B3, is a powerhouse ingredient in skincare celebrated for its wide range of benefits. This water-soluble vitamin helps to strengthen the skin's barrier function, reducing moisture loss and enhancing its ability to retain hydration. Niacinamide also has anti-inflammatory properties, which can help soothe redness, irritation, and acne. Additionally, it regulates sebum production, making it beneficial for oily or acne-prone skin types. Furthermore, niacinamide has been shown to reduce the appearance of hyperpigmentation, fine lines, and wrinkles, promoting a smoother and more even complexion. Its versatility and gentle nature make niacinamide suitable for all skin types, making it a popular ingredient in serums, moisturizers, and other skincare products.

Reduction of Redness and Blotchiness

Niacinamide helps to strengthen the skin's natural barrier, reducing sensitivity and improving its ability to retain moisture. This can lead to a reduction in redness and blotchiness associated with sensitive skin (Draelos, 2006).

Reduction of Sebum Production

Niacinamide has been shown to reduce sebum production in individuals with oily skin, leading to a matte appearance and reduced shine (Draelos, 2006).

Reduction of Fine Lines and Wrinkles

Niacinamide stimulates collagen synthesis and dermal protein production, leading to improvements in fine lines, wrinkles, and overall skin elasticity. It also helps to inhibit glycation, a process that contributes to skin aging (Bissett et al., 2005).

Reduction of Skin Yellowing

Niacinamide has been shown to reduce skin yellowing and sallowness associated with aging. It helps improve overall skin tone and radiance (Bissett et al., 2007).

Barrier Function Improvement

Niacinamide enhances the skin's barrier function by increasing ceramide and free fatty acid levels in the stratum corneum. This helps strengthen the skin barrier, reducing trans-epidermal water loss and improving moisture retention (Gehring, 2004).

Anti-Inflammatory Effects

Niacinamide exhibits potent anti-inflammatory properties, helping to calm and soothe inflamed skin. It can be beneficial for conditions such as acne, rosacea, and eczema (Draelos, 2006).

Oil Control for Acne-Prone Skin

Niacinamide regulates sebum production by inhibiting the sebaceous gland lipogenesis. This can help reduce excess oiliness in acne-prone skin without causing dryness (Draelos, 2006).

Treatment of Hyperpigmentation Disorders

Niacinamide is effective in treating various hyperpigmentation disorders, including melasma and post-inflammatory hyperpigmentation. It acts by inhibiting melanin transfer and reducing melanosome production (Hakozaki et al., 2002).

Antioxidant Protection

Niacinamide possesses antioxidant properties, protecting the skin from oxidative stress and environmental damage caused by free radicals. It helps maintain skin health and vitality (Namazi & Pourmokhtari, 2019).

Reduction of Hyperpigmentation

Niacinamide is effective in reducing hyperpigmentation by inhibiting melanosome transfer from melanocytes to keratinocytes. It also helps to inhibit the production of melanin, leading to a more even skin tone (Bissett et al., 2007).

Prevention of Photodamage

Niacinamide has photoprotective properties, protecting the skin from UV-induced damage. It helps repair DNA damage caused by UV radiation and prevents immunosuppression in the skin (Namazi & Pourmokhtari, 2019).

Enhancement of Skin Hydration

Niacinamide improves skin hydration by increasing the synthesis of ceramides, which are essential for maintaining the skin's moisture barrier. It helps prevent water loss and keeps the skin hydrated and supple (Gehring, 2004).

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